Description

4,6-Dichloro-1H-Pyrrolo[2,3-B]Pyridine is a high-value halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key intermediate for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring functionalized pyrrolopyridine scaffolds.

Basic Information

Product Name	4,6-Dichloro-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	5912-18-5
Molecular Formula	C7H4Cl2N2
Molecular Weight	187.03 g/mol
Synonyms	4,6-Dichloro-7-azaindole; 4,6-Dichloro-1H-pyrrolo[2,3-b]pyridine; 4,6-Dichloro-1H-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 4,6-dichloro-; 4,6-Dichloro-7-aza-indole; 4,6-Dichloro-1H-pyrrolo[2,3-b]pyridine; 4,6-Dichloroazaindole
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (HPLC), identity (IR, NMR), and impurity profiles. Our quality management system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.