Description

Phenyl(Trimethylsilyl)Methanone (CAS NO 5908-41-8) is a versatile organosilicon compound featuring a benzoyl group protected by a trimethylsilyl moiety. This structure makes it a valuable silyl ketone reagent and a key synthetic intermediate in advanced organic synthesis. It is primarily used by pharmaceutical, agrochemical, and advanced materials research and development teams for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing ketone functionalities in a protected form.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides requiring specific silicon-containing ketone structures.
• Organometallic Chemistry: Serves as a precursor or ligand in the preparation of metal-organic complexes and catalysts.
• Material Science Research: Employed in the development of novel silicon-based polymers, resins, and specialty coatings.
• Organic Synthesis Reagent: Acts as a protected benzoyl anion equivalent or a silyl transfer agent in multi-step synthetic routes.
• Laboratory Research & Development: A critical reagent for academic and industrial R&D in methodology development and complex molecule construction.

Basic Information

Product Name	Phenyl(Trimethylsilyl)Methanone
CAS No.	5908-41-8
Molecular Formula	C10H14OSi
Molecular Weight	178.30 g/mol
Synonyms	Trimethyl(phenacyl)silane; Benzoyltrimethylsilane; Phenacyltrimethylsilane; (Phenacyl)trimethylsilane; Trimethylsilyl phenyl ketone; α-Trimethylsilylacetophenone; (Trimethylsilyl)(phenyl)methanone; TMS-Phenyl Ketone
EINECS	227-625-6

Quality Control

Our Phenyl(Trimethylsilyl)Methanone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to meet the stringent requirements of our global B2B clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain purity and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.