Description

Rel-(1R*,2R*)-2-Phenylcyclopropane-1-Carboxylic Acid Methyl Ester is a high-purity chiral cyclopropane derivative, a crucial building block in advanced organic synthesis. Its rigid, strained three-membered ring structure and defined stereochemistry make it an invaluable intermediate for constructing complex molecules with precise spatial orientation. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and cardiovascular diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring contributes to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Material Science Research: Employed in the development of novel polymers and advanced organic materials with specific structural properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including cyclopropanation reactions and stereoselective transformations.

Basic Information

Product Name	Rel-(1R*,2R*)-2-Phenylcyclopropane-1-Carboxylic Acid Methyl Ester
CAS No.	5861-31-4
Molecular Formula	C11H12O2
Molecular Weight	176.21 g/mol
Synonyms	Methyl (1R*,2R*)-2-phenylcyclopropanecarboxylate; Methyl rel-(1R,2R)-2-phenylcyclopropanecarboxylate; Methyl trans-2-phenylcyclopropanecarboxylate; 2-Phenylcyclopropanecarboxylic acid methyl ester; trans-Methyl 2-phenylcyclopropanecarboxylate; (1R*,2R*)-Methyl 2-phenylcyclopropanecarboxylate; Methyl (1R,2R)-2-phenylcyclopropanecarboxylate (rel)
EINECS	Contact for details

Quality Control

Our Rel-(1R*,2R*)-2-Phenylcyclopropane-1-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (diastereomeric ratio)	≥ 95:5 (trans:cis)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.