Description

Dimethyl 2-(Trifluoromethyl)Propanedioate is a versatile fluorinated building block, specifically a diester of a trifluoromethyl-substituted malonic acid derivative. Its value lies in its ability to introduce the highly desirable trifluoromethyl group into complex molecules, significantly altering their physical, chemical, and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, serving as a key intermediate in the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) containing the CF₃ group, which enhances metabolic stability, lipophilicity, and bioavailability.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Organic Synthesis Building Block: Employed in various carbon-carbon bond-forming reactions, such as malonic ester syntheses, Knoevenagel condensations, and Michael additions.
• Liquid Crystal & OLED Material Research: Serves as a starting material for creating fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Fluorinated Polymer & Coating Monomers: Acts as a monomer or modifier in the production of specialty polymers with enhanced chemical resistance, durability, and surface properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry R&D to explore new chemical entities and optimize synthetic routes.

Basic Information

Product Name	Dimethyl 2-(Trifluoromethyl)Propanedioate
CAS No.	5838-00-6
Molecular Formula	C₆H₇F₃O₄
Molecular Weight	200.12 g/mol
Synonyms	Dimethyl (Trifluoromethyl)malonate; Methyl (Trifluoromethyl)malonate; Propanedioic acid, 2-(trifluoromethyl)-, dimethyl ester; (Trifluoromethyl)malonic Acid Dimethyl Ester; Dimethyl Trifluoromethylmalonate; 2-(Trifluoromethyl)malonic Acid Dimethyl Ester; Trifluoromethylmalonic Acid Dimethyl Ester; Dimethyl α-Trifluoromethylmalonate
EINECS	Contact for details

Quality Control

Our Dimethyl 2-(Trifluoromethyl)Propanedioate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets precise customer specifications and industry standards. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical properties are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.390 - 1.400
Density	1.35 - 1.45 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.