Description

2-Trimethylsilanyloxy-Ethylamine is a versatile organosilicon compound featuring a reactive amine group protected by a trimethylsilyl (TMS) ether moiety. This unique bifunctional structure makes it a valuable silylating agent and protected intermediate in sophisticated organic synthesis. It is primarily sought after by pharmaceutical, agrochemical, and advanced material researchers for constructing complex molecules, modifying surfaces, and developing silicon-based polymers where controlled amine functionality is required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly where a protected aminoethanol derivative is needed.
• Agrochemical Synthesis: Serves as a key building block for creating herbicides, fungicides, and plant growth regulators with enhanced properties.
• Surface Modification Agent: Employed to functionalize silica, glass, or other oxide surfaces, imparting amine groups for further chemical attachment.
• Polymer & Silicone Chemistry: Acts as a monomer or cross-linking agent in the production of specialty silicones and hybrid organic-inorganic polymers.
• Peptide Synthesis: Utilized as a protecting group for hydroxyl functions on serine or threonine analogs during solid-phase peptide synthesis.
• Catalyst & Ligand Preparation: Used to synthesize novel organosilicon-based ligands for transition metal catalysis.

Basic Information

Product Name	2-Trimethylsilanyloxy-Ethylamine
CAS No.	5804-92-2
Molecular Formula	C7H19NOSi
Molecular Weight	161.32 g/mol
Synonyms	2-[(Trimethylsilyl)oxy]ethanamine; 2-Aminoethyloxytrimethylsilane; N-(2-Hydroxyethyl)trimethylsilylamine; O-Trimethylsilylethanolamine; 2-(Trimethylsiloxy)ethylamine; β-Trimethylsiloxyethylamine; (2-Aminoethoxy)trimethylsilane; Aminoethyl alcohol trimethylsilyl ether
EINECS	227-366-1

Quality Control

Our 2-Trimethylsilanyloxy-Ethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4180 - 1.4220
Density (20°C)	0.86 - 0.90 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.