Description

Ethynyl Estradiol 3-Acetate is a synthetic steroidal estrogen derivative, specifically the 3-acetate ester of ethynyl estradiol. This compound is a critical pharmaceutical intermediate valued for its high purity and consistent performance in complex synthesis pathways. It is primarily required by manufacturers in the pharmaceutical and life sciences sectors for the development and production of steroidal hormone-based medications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of various steroidal drugs and hormone therapies.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the manufacturing process of specific estrogen-based APIs.
• Research & Development: Serves as a reference standard and starting material in biochemical and pharmacological research.
• Contraceptive Formulations: Employed in the development of certain hormonal contraceptive agents.
• Hormone Replacement Therapy (HRT): A precursor in the production of medications used for menopausal symptom management.

Basic Information

Product Name	Ethynyl Estradiol 3-Acetate
CAS No.	5779-47-5
Molecular Formula	C22H28O3
Molecular Weight	340.46 g/mol
Synonyms	19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol 3-acetate; 17α-Ethynylestradiol 3-acetate; EE 3-Acetate; Ethinyl Estradiol Acetate; 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol 3-acetate; 3-Acetoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-yn-17-ol
EINECS	Contact for details

Quality Control

Our Ethynyl Estradiol 3-Acetate is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical intermediates. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.