Description

3,5,6,7-Tetrahydrospiro[4H-Cyclopentapyrimidine-4,1'-Cyclopentane]-2(1H)-Thione is a sophisticated spirocyclic thiopyrimidine derivative, a high-value building block prized for its unique fused-ring scaffold. This compound matters for its role as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, enabling the exploration of new chemical space. Pharmaceutical R&D teams and fine chemical manufacturers need this high-purity intermediate to develop next-generation therapeutic agents and specialty products.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with novel modes of action.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex heterocyclic compounds and spirocyclic frameworks.
• Material Science Research: Investigated as a precursor for specialty chemicals and functional materials.
• Contract Research & Development (CRO/CMO): Supplied to service organizations for client-directed custom synthesis projects.

Basic Information

Product Name	3,5,6,7-Tetrahydrospiro[4H-Cyclopentapyrimidine-4,1'-Cyclopentane]-2(1H)-Thione
CAS No.	5778-25-6
Molecular Formula	C11H14N2S
Molecular Weight	206.31 g/mol
Synonyms	Spiro[cyclopentane-1,4'-[4H]cyclopentapyrimidine]-2'(1'H)-thione, 3',5',6',7'-Tetrahydro-; 3,5,6,7-Tetrahydrospiro[cyclopentapyrimidine-4,1'-cyclopentane]-2(1H)-thione; 2-Thioxo-1,2,3,5,6,7-hexahydrospiro[cyclopentapyrimidine-4,1'-cyclopentane]; Spirocyclic thiopyrimidine; Tetrahydrospirocyclopentapyrimidinthione
EINECS	Contact for details

Quality Control

Our 3,5,6,7-Tetrahydrospiro[4H-Cyclopentapyrimidine-4,1'-Cyclopentane]-2(1H)-Thione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.