Description

Estra-1,3,5(10)-Triene-3,17Beta-Diol 17-Palmitate is a high-purity steroid ester, specifically the palmitate ester of estradiol. This compound is valued for its enhanced stability and lipophilic properties compared to the parent hormone, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by research institutions and manufacturers in the pharmaceutical and life sciences sectors for the development and production of specialized hormonal therapies and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of specialized steroidal active pharmaceutical ingredients (APIs) and prodrugs.
• Research & Development: Used as a reference standard and biochemical tool in endocrine research, pharmacology, and metabolic studies.
• Controlled-Release Formulations: Its lipophilic nature makes it suitable for research into depot or long-acting injectable hormonal formulations.
• Biochemical Synthesis: Serves as a protected or modified intermediate in complex organic and steroidal synthesis pathways.
• Analytical Standard: Employed for method development, calibration, and quality control testing in analytical laboratories.

Basic Information

Product Name	Estra-1,3,5(10)-Triene-3,17Beta-Diol 17-Palmitate
CAS No.	5776-45-4
Molecular Formula	C34H54O3
Molecular Weight	510.80 g/mol
Synonyms	Estradiol 17-Palmitate; 17β-Estradiol 17-Palmitate; Estra-1,3,5(10)-triene-3,17β-diol 17-hexadecanoate; 3-Hydroxy-1,3,5(10)-estratrien-17β-yl palmitate; NSC 17591; Oestradiol Monopalmitate
EINECS	227-317-5

Quality Control

Our Estra-1,3,5(10)-Triene-3,17Beta-Diol 17-Palmitate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.