Description

4-Chlorobenzenesulfonyl Isocyanate is a versatile and highly reactive chemical building block used in the synthesis of sulfonylurea derivatives. This compound matters for its role as a key intermediate in creating molecules with specific biological and material science applications, offering precise functionalization. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries, as well as by manufacturers of specialty polymers and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonylurea-based drugs, including certain classes of antidiabetic and diuretic agents.
• Agrochemical Synthesis: Used in the development of modern herbicides and pesticides that act via specific enzyme inhibition pathways.
• Polymer Modification: Serves as a reactive monomer or cross-linking agent to introduce sulfonyl isocyanate functional groups into polymer chains, enhancing material properties.
• Chemical Research & Development: A valuable reagent in organic synthesis for constructing complex molecules, particularly in medicinal chemistry and material science projects.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other specialty chemicals requiring the sulfonyl isocyanate moiety.

Basic Information

Product Name	4-Chlorobenzenesulfonyl Isocyanate
CAS No.	5769-15-3
Molecular Formula	C7H4ClNO3S
Molecular Weight	217.63 g/mol
Synonyms	p-Chlorobenzenesulfonyl isocyanate; 4-Chlorobenzene-1-sulfonyl isocyanate; Benzenesulfonyl isocyanate, 4-chloro-; 1-Chloro-4-(isocyanatosulfonyl)benzene; 4-Chlorophenylsulfonyl isocyanate; NSC 163081; 4-CBSI
EINECS	227-300-7

Quality Control

Our 4-Chlorobenzenesulfonyl Isocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practices (cGMP) where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with global regulatory standards, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.