Description

tert-Butyl (1S,2S,5R)-5-Chloro-2-Methyl-Cyclohexane-1-Carboxylate is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. This compound matters because its specific stereochemistry and functional groups make it a valuable building block for constructing complex molecules with precise three-dimensional architecture. It is primarily needed by research and development chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for constructing complex, stereocentered molecular frameworks.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Process Chemistry: Employed in route scouting and scale-up processes for the manufacture of fine chemicals and specialty materials.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry, exploring new synthetic transformations and reaction mechanisms.
• Custom Synthesis Projects: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.

Basic Information

Product Name	tert-Butyl (1S,2S,5R)-5-Chloro-2-Methyl-Cyclohexane-1-Carboxylate
CAS No.	5748-22-1
Molecular Formula	C12H21ClO2
Molecular Weight	232.75 g/mol
Synonyms	(1S,2S,5R)-5-Chloro-2-methylcyclohexane-1-carboxylic acid tert-butyl ester; tert-Butyl 5-chloro-2-methylcyclohexanecarboxylate (stereoisomer); (1S,2S,5R)-rel-5-Chloro-2-methylcyclohexanecarboxylic acid 1,1-dimethylethyl ester; 5-Chloro-2-methylcyclohexanecarboxylic acid tert-butyl ester, (1S,2S,5R)-; Chiral tert-butyl cyclohexanecarboxylate derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl (1S,2S,5R)-5-Chloro-2-Methyl-Cyclohexane-1-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee consistent quality, identity, and purity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.