Description

2-Dimethylaminopyridine (CAS NO 5683-33-0) is a versatile and highly effective nucleophilic catalyst and acyl transfer agent. Its primary value lies in accelerating acylation and alkylation reactions under mild conditions, often with superior selectivity and yield compared to other catalysts like pyridine. This compound is essential for research chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require efficient synthesis of complex organic molecules.

Application

• Pharmaceutical Synthesis: A key catalyst in the production of active pharmaceutical ingredients (APIs), particularly for acylation reactions in peptide coupling and esterification.
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and insecticides where selective acylation is required.
• Polymer Chemistry: Acts as a catalyst in the synthesis of polyesters, polyamides, and other specialty polymers.
• Fine Chemical Production: Facilitates the synthesis of dyes, fragrances, and photographic chemicals.
• Academic & Industrial R&D: A staple reagent in organic synthesis laboratories for method development and scale-up studies.
• Peptide Synthesis: Employed as a coupling agent to form amide bonds, enhancing reaction rates and reducing racemization.

Basic Information

Product Name	2-Dimethylaminopyridine
CAS No.	5683-33-0
Molecular Formula	C7H10N2
Molecular Weight	122.17 g/mol
Synonyms	DMAP; N,N-Dimethyl-4-aminopyridine; 4-Dimethylaminopyridine; 4-(Dimethylamino)pyridine; N,N-Dimethylpyridin-4-amine; 4-Pyridinamine, N,N-dimethyl-; Catalyst DMAP; p-Dimethylaminopyridine
EINECS	227-139-1

Quality Control

Our 2-Dimethylaminopyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthesis and catalysis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from atmospheric moisture and should be stored away from direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.