Description

3-(Trimethylsilyl)Propiolic Acid is a versatile organosilicon building block featuring both a silyl-protected alkyne and a carboxylic acid functional group. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules in advanced research and industrial applications. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for constructing novel compounds, including active pharmaceutical ingredients (APIs), specialty polymers, and advanced ligands.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those requiring alkyne or silyl-protected functional groups.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, silicon-based coatings, and advanced composite materials.
• Organic Synthesis Reagent: A valuable reagent for Sonogashira coupling reactions and other cross-coupling methodologies to create carbon-carbon bonds.
• Ligand Precursor: Utilized in the preparation of sophisticated ligands for catalysis and coordination chemistry.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic pathways and creating novel molecular architectures.

Basic Information

Product Name	3-(Trimethylsilyl)Propiolic Acid
CAS No.	5683-31-8
Molecular Formula	C6H10O2Si
Molecular Weight	142.23 g/mol
Synonyms	3-(Trimethylsilyl)prop-2-ynoic acid; Trimethylsilylpropiolic acid; Propiolic acid, 3-(trimethylsilyl)-; TMS-Propiolic Acid; 2-Propynoic acid, 3-(trimethylsilyl)-; 3-(Trimethylsilyl)-2-propynoic acid
EINECS	227-126-3

Quality Control

Our 3-(Trimethylsilyl)Propiolic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.