Description

3-(Trimethylsilyl) Propionic Acid is a versatile organosilicon compound that serves as a key building block and protective group reagent in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a silyl group, makes it invaluable for modifying molecular properties and facilitating complex chemical transformations. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking reliable, high-quality raw materials for their processes.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly as a protecting group for carboxylic acids or as a precursor for prodrug development.
• Polymer & Material Science: Acts as a monomer or surface-modifying agent to create silicone-containing polymers, coatings, and adhesives with enhanced properties.
• Agrochemical Synthesis: Employed in the production of advanced pesticides and herbicides where the silyl group aids in delivery or stability.
• NMR Spectroscopy: Serves as an internal chemical shift reference standard (TSP) in deuterated solvents for nuclear magnetic resonance analysis.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing the trimethylsilylpropionyl moiety or for temporary protection of functional groups.
• Surface Modification: Used to functionalize silica, glass, or other inorganic surfaces to alter hydrophobicity and reactivity.

Basic Information

Product Name	3-(Trimethylsilyl) Propionic Acid
CAS No.	5683-30-7
Molecular Formula	C6H14O2Si
Molecular Weight	146.26 g/mol
Synonyms	3-(Trimethylsilyl)propanoic Acid; Trimethylsilylpropionic Acid; TSP; 3-(Trimethylsilyl)propionic Acid-d4; (3-Carboxypropyl)trimethylsilane; NSC 334368; 3-(Trimethylsilyl)propionic Acid Sodium Salt; TSP-d4
EINECS	227-139-5

Quality Control

Our 3-(Trimethylsilyl) Propionic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.