Description

(S)-2-Benzyloxycarbonylamino-Pentanedioic Acid 5-Benzyl Ester is a high-purity, chiral protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block for the controlled construction of peptides and complex molecules, offering precise stereochemical control. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide-based drugs, and fine chemical intermediates.

Application

• Peptide Synthesis: A key chiral intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Pharmaceutical Research: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those requiring specific (S)-glutamic acid derivatives.
• Protecting Group Chemistry: The benzyloxycarbonyl (Cbz) and benzyl ester groups allow for selective deprotection strategies in multi-step synthetic routes.
• Bioconjugation: Acts as a linker or spacer molecule in the design of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and probes for studying biological processes and enzyme mechanisms.
• Fine Chemical Production: Serves as a precursor for the manufacture of specialty chemicals, catalysts, and ligands used in asymmetric synthesis.

Basic Information

Product Name	(S)-2-Benzyloxycarbonylamino-Pentanedioic Acid 5-Benzyl Ester
CAS No.	5680-86-4
Molecular Formula	C20H21NO6
Molecular Weight	371.39 g/mol
Synonyms	H-Glu(OBzl)-OBzl; (S)-2-(((Benzyloxy)carbonyl)amino)pentanedioic acid 5-benzyl ester; N-Cbz-L-glutamic acid α-benzyl ester; N-Cbz-L-glutamic acid 5-benzyl ester; Z-L-Glu(OBzl)-OH; Z-L-Glutamic Acid 5-Benzyl Ester; L-Glutamic acid, N-[(benzyloxy)carbonyl]-, 5-benzyl ester; N-Carbobenzoxy-L-glutamic acid α-benzyl ester
EINECS	Contact for details

Quality Control

Our (S)-2-Benzyloxycarbonylamino-Pentanedioic Acid 5-Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.