Description

L-Serine Methyl Ester Hydrochloride is a protected amino acid derivative essential for advanced organic synthesis and peptide chemistry. This high-purity building block is critical for researchers and manufacturers requiring precise control over molecular structure and chirality. It is primarily utilized in the pharmaceutical industry for the development of active pharmaceutical ingredients (APIs), peptide-based therapeutics, and complex biochemical research.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) and therapeutic peptides.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected serine residue to prevent unwanted side reactions.
• Biochemical Research: Serves as a precursor or substrate in enzymatic studies and metabolic pathway investigations.
• Proteomics & Bioconjugation: Facilitates the site-specific modification of proteins and the creation of peptide-based diagnostic tools.
• Agrochemical Development: Employed in the research and synthesis of advanced, biologically active compounds.
• Academic & R&D Laboratories: A standard reagent for organic chemistry research, method development, and teaching advanced synthesis techniques.

Basic Information

Item	Detail
Product Name	L-Serine Methyl Ester Hydrochloride
CAS No.	5680-80-8
Molecular Formula	C4H10ClNO3
Molecular Weight	155.58 g/mol
Synonyms	L-Serine Methyl Ester HCl; (S)-2-Amino-3-hydroxypropanoic Acid Methyl Ester Hydrochloride; Methyl L-Serinate Hydrochloride; Serine Methyl Ester Hydrochloride; H-Ser-OMe·HCl; (S)-Serine Methyl Ester Hydrochloride; L-Ser-OMe·HCl; Methyl (S)-2-amino-3-hydroxypropanoate hydrochloride
EINECS	Contact for details

Quality Control

Our L-Serine Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+14.0° to +16.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.