Description

Z-Glu-Ome is a protected glutamic acid derivative, specifically the benzyloxycarbonyl (Z) protected methyl ester of L-glutamic acid. This compound is a crucial building block in peptide synthesis, offering a versatile handle for the controlled elongation of peptide chains. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides and for biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential addition of glutamic acid residues.
• Solution-Phase Peptide Synthesis: Used in classical methods for constructing specific peptide sequences.
• Pharmaceutical Intermediate: Serves as a precursor in the synthesis of peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies of enzyme-substrate interactions, receptor binding, and protein structure-function relationships.
• Protecting Group Chemistry: Demonstrates the application of Z (Cbz) and methyl ester protecting groups in synthetic organic chemistry.
• Custom Peptide Service: A fundamental reagent for contract research organizations (CROs) and CDMOs offering bespoke peptide manufacturing.

Basic Information

Product Name	Z-Glu-Ome
CAS No.	5672-83-3
Molecular Formula	C14H17NO6
Molecular Weight	295.29 g/mol
Synonyms	N-Carbobenzoxy-L-glutamic acid α-methyl ester; N-Cbz-L-glutamic acid 1-methyl ester; Z-L-Glutamic acid α-methyl ester; (S)-2-(((Benzyloxy)carbonyl)amino)pentanedioic acid 1-methyl ester; Cbz-Glu-OMe; Nα-Carbobenzyloxy-L-glutamic acid methyl ester; Benzyl N-[(1S)-4-methoxy-1,4-dioxobutan-2-yl]carbamate
EINECS	Contact for details

Quality Control

Our Z-Glu-Ome CAS NO 5672-83-3 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements for peptide synthesis. Certificates of Analysis (COA) detailing purity, identity, and specific impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.