Description

2-Hydroxy-3-Amino-5-Nitropyridine is a versatile heterocyclic compound featuring a unique combination of hydroxy, amino, and nitro functional groups on a pyridine scaffold. This multi-functional structure makes it a valuable intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research and development chemists, process engineers, and manufacturers in fine chemical and active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, including potential kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its nitro and amino groups for further chemical modifications.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other complex colorants due to its aromatic amine functionality.
• Coordination Chemistry & Ligand Synthesis: The hydroxy and amino groups can act as donor atoms for creating metal-organic complexes and catalysts.
• Research & Development: Employed in academic and industrial R&D for exploring new chemical reactions and material properties.
• Fine Chemical Production: An intermediate for various specialty chemicals requiring a functionalized nitropyridine core.

Basic Information

Product Name	2-Hydroxy-3-Amino-5-Nitropyridine
CAS No.	5667-38-9
Molecular Formula	C5H5N3O3
Molecular Weight	155.11 g/mol
Synonyms	3-Amino-5-nitro-2-pyridinol; 3-Amino-5-nitro-2(1H)-pyridinone; 5-Nitro-3-aminopyridin-2-ol; 2-Pyridinol, 3-amino-5-nitro-; 3-Amino-5-nitropyridin-2-ol; 2-Hydroxy-3-amino-5-nitropyridine; 5-Nitro-3-amino-2-pyridone
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Amino-5-Nitropyridine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay by HPLC, identification by FT-IR, and control of related substances. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.