Description

2-Chloro-3,5-Diaminopyridine is a versatile halogenated diaminopyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive chlorine substituent and two amine groups, makes it a valuable precursor for constructing complex heterocyclic systems and functional materials. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active compounds and performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, kinase inhibitors, and anti-infective agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and plant growth regulators, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a chelating agent or precursor for ligands in transition metal catalysis and coordination chemistry.
• Polymer and Material Science: Building block for high-performance polymers, dyes, pigments, and electronic materials due to its aromaticity and functional handles.
• Chemical Research & Development: Fundamental reagent for exploring novel heterocyclic chemistry and developing new synthetic methodologies in academic and industrial labs.

Basic Information

Product Name	2-Chloro-3,5-Diaminopyridine
CAS No.	5632-81-5
Molecular Formula	C5H6ClN3
Molecular Weight	143.57 g/mol
Synonyms	3,5-Diamino-2-chloropyridine; 2-Chloro-3,5-pyridinediamine; 2-Chloropyridine-3,5-diamine; 3,5-Diamino-2-chloro-pyridine; 2-Chloro-3,5-diamino pyridine; 2-Chloro-3,5-bis(amino)pyridine; 2-Cl-3,5-(NH2)2Py
EINECS	227-076-7

Quality Control

Our 2-Chloro-3,5-Diaminopyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications, ensuring reliable supply chain integrity for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.