Description

N,n-Bis(Trimethylsilyl)Glycine Trimethylsilyl Ester CAS NO 5630-82-0 is a specialized organosilicon derivative of glycine, extensively used as a key silylating agent and synthetic intermediate. Its primary value lies in its ability to protect amino and carboxyl groups, facilitating complex organic syntheses and derivatization processes for analytical chemistry. This high-purity reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance building blocks for sensitive reactions.

Application

• Pharmaceutical Intermediate: Used in the synthesis of protected amino acid derivatives for peptide and active pharmaceutical ingredient (API) development.
• Gas Chromatography (GC) Derivatization: Serves as a derivatization agent for glycine and related compounds to enhance their volatility and thermal stability for accurate GC and GC-MS analysis.
• Organosilicon Chemistry: Acts as a versatile precursor for introducing trimethylsilyl groups into complex molecular architectures.
• Agrochemical Synthesis: Employed as a building block in the production of specialized herbicides, fungicides, and plant growth regulators.
• Material Science Research: Utilized in the development of novel silicon-containing polymers and hybrid organic-inorganic materials.
• Analytical Reference Standard: Provides a high-purity standard for method development and quality control in analytical laboratories.

Basic Information

Product Name	N,n-Bis(Trimethylsilyl)Glycine Trimethylsilyl Ester
CAS No.	5630-82-0
Molecular Formula	C11H27NO2Si3
Molecular Weight	289.59 g/mol
Synonyms	Glycine, N,N-bis(trimethylsilyl)-, trimethylsilyl ester; Trimethylsilyl N,N-bis(trimethylsilyl)glycinate; BTS Glycine; N,N-Bis(trimethylsilyl)glycine TMS ester; (Trimethylsilyl) 2,2-bis(trimethylsilylamino)acetate; Glycine TMS derivative; TMS-Gly-OTMS
EINECS	227-076-1

Quality Control

Our N,n-Bis(Trimethylsilyl)Glycine Trimethylsilyl Ester is manufactured under controlled conditions to ensure batch-to-batch consistency and high chemical purity. Quality is verified through a comprehensive suite of analytical techniques including GC, NMR, and Karl Fischer titration. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.