Description

2-Methyleneglutaric Acid Diethyl Ester is a versatile diester compound with a reactive methylene group, serving as a key building block in organic synthesis. Its value lies in its bifunctional nature, offering both ester functionalities and an activated alkene site for Michael additions and other C-C bond-forming reactions. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those requiring glutaric acid derivatives or functionalized scaffolds.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that incorporate modified glutaric acid structures.
• Polymer & Resin Modifier: Acts as a cross-linking agent or a monomer for specialty polymers, enhancing properties like flexibility, adhesion, or chemical resistance.
• Organic Synthesis Building Block: Employed in Michael addition reactions, cyclizations, and ester transformations to construct more complex molecular architectures in R&D settings.
• Flavor & Fragrance Ingredient Synthesis: Serves as an intermediate for creating esters and lactones used in high-value aroma chemicals.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and developing novel compounds in academic and industrial laboratories.

Basic Information

Product Name	2-Methyleneglutaric Acid Diethyl Ester
CAS No.	5621-43-2
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	Diethyl 2-Methyleneglutarate; Diethyl 2-Methylene-1,5-pentanedioate; 2-Methylene-pentanedioic Acid Diethyl Ester; Glutaric Acid, 2-Methylene-, Diethyl Ester; Ethyl 2-Methyleneglutarate; NSC 33436
EINECS	227-055-5

Quality Control

Our 2-Methyleneglutaric Acid Diethyl Ester is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the rigorous standards required for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.