Description

Triphenylsilylazide is a versatile organosilicon reagent featuring a reactive azide functional group. This compound is valued for its role as a safe and effective reagent for the introduction of azide groups and for participating in click chemistry and Staudinger reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel compounds and functionalizing complex molecules.

Application

• Key reagent in Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry for bioconjugation and polymer synthesis.
• Precursor for the synthesis of silyl-protected amines via Staudinger reduction or other transformations.
• Used in the preparation of heterocyclic compounds, including triazoles and tetrazoles, for medicinal chemistry applications.
• Reagent for the azidation of organic halides, tosylates, and epoxides under mild conditions.
• Employed in material science for the surface functionalization of silicon-based substrates and nanoparticles.
• Intermediate in the synthesis of novel organosilicon compounds with potential biological activity.

Basic Information

Product Name	Triphenylsilylazide
CAS No.	5599-34-8
Molecular Formula	C18H15N3Si
Molecular Weight	301.43 g/mol
Synonyms	Azidotriphenylsilane; Triphenylsilyl Azide; Silane, azidotriphenyl-; N3SiPh3; NSC 163082; Azidosilane, triphenyl-; Triphenylsilicon Azide
EINECS	Contact for details

Quality Control

Our Triphenylsilylazide is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and spectroscopic identification, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. Handle and store under an inert atmosphere for optimal shelf life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.