Description

9-Azido-ααα-trifluorotoluene Solution is a specialized organic reagent featuring a reactive azido group and a trifluoromethyl substituent. This unique bifunctional structure makes it a valuable building block for introducing both azide and fluorinated moieties in a single synthetic step, enabling efficient derivatization and click chemistry applications. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bioactive molecules, particularly for incorporating fluorine atoms to modulate metabolic stability and lipophilicity.
• Click Chemistry Reagent: Serves as a versatile partner in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Agrochemical Research: Used in creating novel fluorinated pesticides and herbicides, where the trifluoromethyl group often enhances biological activity.
• Liquid Crystal & OLED Material Development: Acts as a building block for fluorinated aromatic compounds used in electronic and photonic materials.
• Proteomics & Chemical Biology: Employed as a tagging or cross-linking agent for studying protein interactions and cellular processes.
• Polymer Modification: Facilitates the introduction of azide functionalities into polymer backbones for subsequent grafting or cross-linking.

Basic Information

Product Name	9-Azido-ααα-trifluorotoluene Solution
CAS No.	5586-13-0
Molecular Formula	C7H4F3N3
Molecular Weight	187.12 g/mol
Synonyms	α-Azido-α,α,α-trifluorotoluene; (Azidomethyl)trifluorobenzene; 1-Azido-1-(trifluoromethyl)benzene; Benzyl azide, α,α,α-trifluoro-; Trifluoromethyl phenyl azide; 9-Azido-α,α,α-trifluorotoluene; Azido(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 9-Azido-ααα-trifluorotoluene Solution is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by HPLC and impurity profiling, to ensure consistency and high purity suitable for research and process chemistry. A Certificate of Analysis (COA) detailing specific results for purity, solvent content, and identity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures between 2°C and 8°C to minimize decomposition. Keep away from heat, sparks, open flames, and strong oxidizing agents. The container must be kept tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0% (or as per solution concentration)
Solvent	Specified (e.g., Dichloromethane, Toluene)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.