Description

Propargyloxytrimethylsilane is a versatile organosilicon compound featuring a reactive propargyl ether group. This unique structure makes it a valuable building block in organic synthesis and materials science, particularly for introducing silicon-protected propargyl functionality. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries who require high-purity intermediates for click chemistry, cross-coupling reactions, and surface modification.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), especially where silicon is used as a protecting group or directing agent.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, leveraging its reactivity for constructing complex molecular architectures.
• Click Chemistry Reagent: Acts as a precursor in Huisgen cycloaddition (azide-alkyne) reactions for bioconjugation and polymer functionalization.
• Surface Modification Agent: Employed to functionalize silica, glass, or metal oxide surfaces, imparting specific chemical properties for coatings and adhesives.
• Polymer & Resin Modifier: Incorporated into silicone resins and hybrid organic-inorganic polymers to enhance thermal stability, adhesion, or cross-linking density.
• Laboratory Research: A fundamental reagent in organometallic and synthetic organic chemistry research for novel bond-forming methodologies.

Basic Information

Product Name	Propargyloxytrimethylsilane
CAS No.	5582-62-7
Molecular Formula	C6H12OSi
Molecular Weight	128.25 g/mol
Synonyms	Trimethyl(2-propyn-1-yloxy)silane; (Prop-2-yn-1-yloxy)trimethylsilane; Propargyl Trimethylsilyl Ether; 2-Propynyloxytrimethylsilane; O-Propargyl Trimethylsilyl Ether; Trimethylsilyl Propargyl Ether; TMS Propargyl Ether
EINECS	226-980-5

Quality Control

Our Propargyloxytrimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.