Description

2-Amino-4-(4-Chlorophenyl)-6-Phenylnicotinonitrile is a high-value, multi-functional chemical intermediate characterized by its unique pyridine core substituted with amino, cyano, and aryl groups. This compound matters for its critical role in the synthesis of complex heterocyclic systems, enabling the development of advanced materials and active pharmaceutical ingredients. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential kinase inhibitors, receptor antagonists, and other biologically active nitrogen-containing heterocycles.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its chlorophenyl and nitrile functionalities.
• Material Science Precursor: Serves as a starting material for creating specialized dyes, pigments, and organic electronic materials due to its conjugated system.
• Chemical Synthesis Reagent: Employed in academic and industrial R&D for constructing complex polycyclic frameworks via cyclization and cross-coupling reactions.
• Ligand and Catalyst Development: The amino and cyano groups make it a useful precursor for synthesizing novel chelating ligands and organocatalysts.

Basic Information

Product Name	2-Amino-4-(4-Chlorophenyl)-6-Phenylnicotinonitrile
CAS No.	5579-40-8
Molecular Formula	C18H12ClN3
Molecular Weight	305.76 g/mol
Synonyms	2-Amino-4-(4-chlorophenyl)-6-phenyl-3-cyanopyridine; 2-Amino-4-(p-chlorophenyl)-6-phenylnicotinonitrile; 3-Cyano-2-amino-4-(4-chlorophenyl)-6-phenylpyridine; 4-(4-Chlorophenyl)-2-amino-6-phenyl-3-pyridinecarbonitrile; 2-Amino-4-(4'-chlorophenyl)-6-phenyl-3-cyanopyridine; 6-Phenyl-2-amino-4-(4-chlorophenyl)nicotinonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Chlorophenyl)-6-Phenylnicotinonitrile is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.