Description

Alverine Citrate is a pharmaceutical active ingredient belonging to the class of antispasmodic agents. It is valued for its direct action on the smooth muscle of the gastrointestinal tract, providing effective relief from spasms and associated pain. This compound is essential for manufacturers in the pharmaceutical industry, particularly for formulating medications targeting irritable bowel syndrome (IBS) and other functional gastrointestinal disorders.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of prescription and over-the-counter antispasmodic medications.
• Irritable Bowel Syndrome (IBS) Treatment: A key component in drugs designed to alleviate abdominal pain, cramping, and bloating associated with IBS.
• Gastrointestinal Spasm Relief: Used in products for treating spasms in the colon, stomach, and other parts of the digestive tract.
• Functional Abdominal Pain Management: Incorporated into therapeutic regimens for chronic functional abdominal pain syndromes.
• Drug Intermediate: Serves as a critical intermediate in the synthesis of more complex pharmaceutical compounds.
• Clinical Research: Utilized as a reference standard or active component in pharmacological studies and clinical trials.

Basic Information

Product Name	Alverine Citrate
CAS No.	5560-59-8
Molecular Formula	C₂₀H₂₇N • C₆H₈O₇
Molecular Weight	473.54 g/mol
Synonyms	Alverine Citrate; Alverine 1,1-Diphenyl-3-piperidin-1-ylpropan-1-ol Citrate; Spacolin; Spasmonal; Prophelan; N-Ethyl-3,3-diphenyl-N-(1-propyl)propylamine Citrate; 1-(3,3-Diphenylpropyl)hexamethyleneimine Citrate; Phenpropanate Citrate
EINECS	226-919-7

Quality Control

Our Alverine Citrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, including identification, assay, and impurity profile checks. Certificates of Analysis (COA) confirming compliance with relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.