Description

3-Hydroxy-5-Phenyl-2-Thiophenecarboxylic Acid Methyl Ester is a high-purity, functionalized thiophene derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique heterocyclic structure, which provides a versatile scaffold for constructing complex molecules with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for use in medicinal chemistry and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators due to its bioactive thiophene core.
• Material Science: Serves as a monomer or functional additive in the research of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses, including cross-coupling reactions and heterocycle formation, to introduce specific functional groups.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-Hydroxy-5-Phenyl-2-Thiophenecarboxylic Acid Methyl Ester
CAS No.	5556-23-0
Molecular Formula	C13H12O3S
Molecular Weight	248.30 g/mol
Synonyms	Methyl 3-hydroxy-5-phenylthiophene-2-carboxylate; 3-Hydroxy-5-phenylthiophene-2-carboxylic acid methyl ester; 5-Phenyl-3-hydroxythiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-hydroxy-5-phenyl-, methyl ester; Methyl 5-phenyl-3-hydroxythiophene-2-carboxylate
EINECS	226-907-4

Quality Control

Our production of 3-Hydroxy-5-Phenyl-2-Thiophenecarboxylic Acid Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up processes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to supporting your regulatory needs and can provide material suitable for use under cGMP guidelines for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.