Description

Rac 8α-[δ-5(10)]-Norgestrel is a synthetic progestin steroid, a key intermediate in the synthesis of various pharmaceutical actives. This compound is valued for its structural role in the development of hormonal therapies and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical industry for the development and production of contraceptive and hormone replacement medications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced progestin-based APIs.
• Contraceptive Drug Development: Used in research and manufacturing of oral contraceptive formulations.
• Hormone Replacement Therapy (HRT): Serves as a precursor in the production of medications for menopausal symptom management.
• Steroid Chemistry Research: A valuable reference standard and starting material for novel steroid synthesis in academic and industrial R&D.
• Veterinary Pharmaceuticals: Employed in the development of hormonal treatments for animal health.

Basic Information

Product Name	Rac 8α-[δ-5(10)]-Norgestrel
CAS No.	5541-87-7
Molecular Formula	C₂₁H₂₈O₂
Molecular Weight	312.45 g/mol
Synonyms	8α-(δ⁵⁽¹⁰⁾)-Norgestrel; 13β-Ethyl-17β-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one; (±)-13β-Ethyl-17β-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one; DL-8α-(δ⁵⁽¹⁰⁾)-Norgestrel; Racemic 8α-(δ⁵⁽¹⁰⁾)-Norgestrel; 17α-Ethynyl-13β-ethyl-17β-hydroxy-4-gonen-3-one; 17α-Ethynyl-18,19-dinor-17β-hydroxy-4-androsten-3-one, 13β-ethyl-
EINECS	226-891-4

Quality Control

Our Rac 8α-[δ-5(10)]-Norgestrel is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.