Description

tert-Butyl 6-Aminohexanoate CAS NO 5514-98-7 is a protected amino acid ester derivative, serving as a crucial building block in organic synthesis. Its value lies in the tert-butyl ester group, which provides excellent stability under various reaction conditions while being readily cleaved under acidic conditions. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the synthesis of peptides, drug candidates, and other complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the 6-aminohexanoic acid (caproic acid) moiety with a protected carboxyl group.
• Linker Chemistry: Serves as a spacer or linker molecule in the development of bioconjugates, antibody-drug conjugates (ADCs), and prodrugs.
• Polymer Modification: Acts as a functional monomer or modifier for creating specialty polymers with amine-reactive sites.
• Organic Synthesis Reagent: Utilized in multi-step synthetic routes to construct complex molecular architectures requiring a protected amino acid functionality.
• Biochemical Research: Employed in proteomics and chemical biology research for labeling and cross-linking applications.

Basic Information

Product Name	tert-Butyl 6-Aminohexanoate
CAS No.	5514-98-7
Molecular Formula	C10H21NO2
Molecular Weight	187.28 g/mol
Synonyms	6-[(tert-Butoxycarbonyl)amino]hexanoic Acid tert-Butyl Ester; 6-Aminohexanoic Acid tert-Butyl Ester; Boc-6-Ahx-OH-tBu; N-Boc-6-Aminohexanoic Acid tert-Butyl Ester; tert-Butyl N-(5-Carboxypentyl)carbamate; 6-(tert-Butoxycarbonylamino)hexanoic Acid tert-Butyl Ester; tert-Butyl 6-[(tert-Butoxycarbonyl)amino]hexanoate (Boc-protected form may be listed); Hexanoic acid, 6-amino-, 1,1-dimethylethyl ester
EINECS	226-864-7

Quality Control

Our tert-Butyl 6-Aminohexanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.