Description

8-[2-(4-Fluorophenyl)Ethyl]-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One is a high-value, spirocyclic organic compound featuring a fluorinated phenyl group. This molecule is a critical advanced intermediate in modern pharmaceutical research and development, prized for its unique structural motif that can impart desirable biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly within central nervous system (CNS) and receptor-targeted therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its spirocyclic and fluorinated pharmacophores.
• Chemical Biology Probe Development: Serves as a core scaffold for developing tool compounds to study specific biological pathways and protein targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Academic Research: Utilized in universities and research institutes for methodological studies in heterocyclic and spiro compound chemistry.

Basic Information

Product Name	8-[2-(4-Fluorophenyl)Ethyl]-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One
CAS No.	5500-76-5
Molecular Formula	C16H21FN2O2
Molecular Weight	292.35 g/mol
Synonyms	1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-[2-(4-fluorophenyl)ethyl]-; 8-(2-(4-Fluorophenyl)ethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one; 5500-76-5; Spiro[4.5]decan-2-one derivative; 4-Fluorophenethyl spirocyclic lactam; Fluorophenyl-diazaspirodecanone
EINECS	Contact for details

Quality Control

Our production of 8-[2-(4-Fluorophenyl)Ethyl]-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for research and development applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.