Description

4-Chloropyridine-2-Carboxylic Acid is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a carboxylic acid group and a chloro-substituted pyridine ring, enabling diverse chemical transformations. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting the central nervous system or possessing antimicrobial properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyridine core is a common bioactive motif.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of functional polymers, metal-organic frameworks (MOFs), and other advanced materials requiring specific molecular architectures.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4-Chloropyridine-2-Carboxylic Acid
CAS No.	5470-22-4
Molecular Formula	C6H4ClNO2
Molecular Weight	157.55 g/mol
Synonyms	2-Carboxy-4-chloropyridine; 4-Chloropicolinic Acid; 4-Chloro-2-pyridinecarboxylic Acid; 2-Pyridinecarboxylic acid, 4-chloro-; Picolinic acid, 4-chloro-; 4-Chloro-2-carboxypyridine
EINECS	226-791-5

Quality Control

Our 4-Chloropyridine-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.