Description

Ethyl 2-Cyclohexylmethylacetoacetate is a versatile β-ketoester derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a cyclohexylmethyl group and an acetoacetate moiety, makes it a valuable precursor for creating complex molecules with specific steric and electronic properties. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a functionalized cyclohexane backbone.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the cyclohexylmethyl group contributes to biological activity and stability.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty organic compounds requiring specific alkyl-acetoacetate structures.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies, such as Claisen condensations and Michael additions.
• Polymer Modifiers: Can be utilized in the synthesis of monomers or additives designed to modify the properties of polymers and resins.

Basic Information

Product Name	Ethyl 2-Cyclohexylmethylacetoacetate
CAS No.	5469-47-6
Molecular Formula	C13H22O3
Molecular Weight	226.31 g/mol
Synonyms	Ethyl 2-(Cyclohexylmethyl)-3-oxobutanoate; Ethyl (2-Cyclohexylmethylaceto)acetate; Acetoacetic Acid, 2-Cyclohexylmethyl-, Ethyl Ester; 3-Oxobutanoic Acid, 2-(Cyclohexylmethyl)-, Ethyl Ester; Ethyl α-Cyclohexylmethylacetoacetate; Ethyl 2-Cyclohexylmethyl-3-oxobutyrate; Ethyl 3-Oxo-2-(cyclohexylmethyl)butanoate
EINECS	226-782-5

Quality Control

Our Ethyl 2-Cyclohexylmethylacetoacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, physical properties, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.460 - 1.470
Density (g/mL at 20°C)	1.010 - 1.030

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.