Description

Benzo[1,3]Dioxol-5-Ylmethyl 2-Chloroacetate is a high-purity organic synthesis intermediate, specifically a chloroacetate ester derivative of a benzodioxole moiety. This compound is valued for its role as a versatile building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those with benzodioxole or related heterocyclic frameworks.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactive chloroacetate group.
• Chemical Research & Development: Serves as a critical reagent for exploring new synthetic pathways and developing novel organic compounds in academic and industrial labs.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including flavors, fragrances, and advanced material precursors.
• Ligand and Catalyst Development: Potential use in creating novel ligands for metal-catalyzed reactions due to its specific functional groups.

Basic Information

Product Name	Benzo[1,3]Dioxol-5-Ylmethyl 2-Chloroacetate
CAS No.	5457-71-6
Molecular Formula	C10H9ClO4
Molecular Weight	228.63 g/mol
Synonyms	1,3-Benzodioxol-5-ylmethyl 2-chloroacetate; 5-(Chloroacetoxymethyl)-1,3-benzodioxole; Piperonyl 2-chloroacetate; 2-Chloroacetic acid 1,3-benzodioxol-5-ylmethyl ester; 2-Chloroacetic acid piperonyl ester; (1,3-Benzodioxol-5-yl)methyl chloroacetate; 5457-71-6; Chloroacetic acid piperonyl ester
EINECS	226-704-6

Quality Control

Our Benzo[1,3]Dioxol-5-Ylmethyl 2-Chloroacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.