Description

Ethyl 2-Hydroxy-3,3-Diphenylpropanoate is a high-value chiral intermediate and building block in organic synthesis. This compound matters for its role in the production of complex molecules, particularly in the pharmaceutical sector where it serves as a precursor for active pharmaceutical ingredients (APIs). Chemical manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and fine chemical industries need this ester for its utility in stereoselective synthesis and as a key fragment in drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of various active pharmaceutical ingredients (APIs), including potential CNS agents and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its diphenylpropanoate structure.
• Fine Chemical Production: Serves as a versatile precursor for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: Employed in chemical research for methodological studies in asymmetric synthesis and catalysis.
• Liquid Crystal & Polymer Chemistry: Investigated as a monomer or additive for advanced materials due to its aromatic and ester functionalities.

Basic Information

Product Name	Ethyl 2-Hydroxy-3,3-Diphenylpropanoate
CAS No.	5449-42-3
Molecular Formula	C17H18O3
Molecular Weight	270.32 g/mol
Synonyms	Ethyl 2-Hydroxy-3,3-diphenylpropionate; 2-Hydroxy-3,3-diphenylpropionic Acid Ethyl Ester; Benzenepropanoic acid, α-hydroxy-β,β-diphenyl-, ethyl ester; Ethyl α-Hydroxy-β,β-diphenylpropionate; Ethyl 3,3-Diphenyl-2-hydroxypropanoate; NSC 403107; Ethyl DL-2-Hydroxy-3,3-diphenylpropionate
EINECS	226-661-2

Quality Control

Our Ethyl 2-Hydroxy-3,3-Diphenylpropanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.