Description

4-Hydroxy-3-Nitropyridine is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, including kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its nitro and hydroxy functional groups for further chemical modification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds.
• Chemical Research & Development: A valuable building block for academic and industrial research into new organic reactions and methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Hydroxy-3-Nitropyridine
CAS No.	5435-54-1
Molecular Formula	C5H4N2O3
Molecular Weight	140.10 g/mol
Synonyms	3-Nitro-4-pyridinol; 3-Nitro-4-hydroxypyridine; 4-Pyridinol, 3-nitro-; 4-Hydroxy-3-nitro-pyridine; 3-Nitro-4(1H)-pyridinone; 4-Hydroxy-3-nitropyridine; 3-Nitropyridin-4-ol; 4-Hydroxy-3-nitro-pyridine
EINECS	226-603-9

Quality Control

Our 4-Hydroxy-3-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere to minimize oxidation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.