Description

1,2,3,4-Tetra-o-Acetyl-A-D-Glucuronidemethylester is a key protected derivative of D-glucuronic acid, serving as a vital synthetic intermediate in carbohydrate and medicinal chemistry. Its value lies in providing a stable, reactive scaffold for the controlled synthesis of complex glycosides, glycoconjugates, and other bioactive molecules. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of glycosylated drugs, prodrugs, and targeted therapeutic agents.
• Carbohydrate Chemistry Research: Used in academic and industrial R&D for constructing complex oligosaccharides and glycoconjugates.
• Glycobiology Studies: Serves as a precursor for labeled probes or standards used in enzymatic and metabolic pathway analysis.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances requiring specific sugar motifs.
• Bioconjugation: Facilitates the attachment of carbohydrate structures to proteins, peptides, or other biomolecules for vaccine and diagnostic kit development.

Basic Information

Product Name	1,2,3,4-Tetra-o-Acetyl-A-D-Glucuronidemethylester
CAS No.	5432-32-6
Molecular Formula	C15H20O12
Molecular Weight	392.31 g/mol
Synonyms	Methyl (2S,3S,4S,5R,6S)-3,4,5-triacetoxy-6-(acetoxymethyl)oxane-2-carboxylate; Methyl 2,3,4-tri-O-acetyl-1-bromo-1-deoxy-α-D-glucopyranuronate; α-D-Glucopyranuronic acid, methyl ester, tetraacetate; 1,2,3,4-Tetra-O-acetyl-α-D-glucuronic acid methyl ester; Tetraacetyl methyl glucuronate; Glucuronic acid methyl ester tetraacetate
EINECS	226-596-8

Quality Control

Our 1,2,3,4-Tetra-o-Acetyl-A-D-Glucuronidemethylester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	[α]20/D: +80° to +90° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.