Description

2-Amino-5-Chloro-3-Nitropyridine is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel compounds and fine-tuning material properties.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various drug candidates, particularly those with pyridine-based cores, such as kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the chloronitropyridine moiety imparts specific biological activity.
• Material Science Research: Serves as a precursor for creating functionalized ligands, organic semiconductors, and other specialty materials requiring precise molecular engineering.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex, high-performance dyes and organic pigments.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and developing novel synthetic methodologies.

Basic Information

Product Name	2-Amino-5-Chloro-3-Nitropyridine
CAS No.	5409-39-2
Molecular Formula	C5H4ClN3O2
Molecular Weight	173.56 g/mol
Synonyms	5-Chloro-3-nitro-2-pyridinamine; 2-Pyridinamine, 5-chloro-3-nitro-; 5-Chloro-3-nitropyridin-2-amine; 2-Amino-5-chloro-3-nitropyridine; 5-Chloro-2-amino-3-nitropyridine; 3-Nitro-5-chloro-2-aminopyridine; 2-AP-5-Cl-3-NO2
EINECS	226-500-8

Quality Control

Our 2-Amino-5-Chloro-3-Nitropyridine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.