Description

Ethyl 4-Amino-3,5-Diiodobenzoate is a high-purity iodinated aromatic ester compound, serving as a critical synthetic intermediate and building block in advanced chemical synthesis. Its value lies in the strategic placement of iodine atoms and the reactive amino and ester functional groups, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of X-ray contrast media agents and other iodinated pharmaceutical compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as a versatile precursor for coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl and conjugated systems.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers due to its halogenated aromatic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical manufacturing and scale-up projects under cGMP or ISO standards.

Basic Information

Product Name	Ethyl 4-Amino-3,5-Diiodobenzoate
CAS No.	5400-81-7
Molecular Formula	C9H9I2NO2
Molecular Weight	416.98 g/mol
Synonyms	Benzoic acid, 4-amino-3,5-diiodo-, ethyl ester; Ethyl 4-amino-3,5-diiodobenzoate; 4-Amino-3,5-diiodobenzoic acid ethyl ester; Ethyl p-amino-3,5-diiodobenzoate; 3,5-Diiodo-4-aminobenzoic acid ethyl ester; AI3-52802; NSC 403697; Ethyl 4-amino-3,5-diiodobenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Amino-3,5-Diiodobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets stringent specifications for research and industrial use. Certificates of Analysis (COA) documenting all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.