Description

Diethyl Isoamylmalonate is a high-purity malonate ester derivative, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in its ability to introduce the isoamylmalonate moiety, enabling the construction of complex molecular frameworks with specific branching patterns. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound development.

Application

• Pharmaceutical Intermediate: Key starting material or building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring branched-chain carboxylic acid derivatives.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the isoamyl group imparts specific biological activity and lipophilicity.
• Fine Chemical Production: Employed in the manufacture of flavors, fragrances, and advanced materials that utilize malonate chemistry.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex molecules via alkylation, condensation, and cyclization reactions.
• Chemical Intermediate: Serves in multi-step synthesis processes to produce other functionalized malonates, acids, and ketones.

Basic Information

Product Name	Diethyl Isoamylmalonate
CAS No.	5398-08-3
Molecular Formula	C12H22O4
Molecular Weight	230.30 g/mol
Synonyms	Diethyl 2-Isoamylmalonate; Isoamylmalonic Acid Diethyl Ester; Diethyl(3-methylbutyl)propanedioate; Diethyl 2-(3-Methylbutyl)malonate; Propanedioic acid, 2-(3-methylbutyl)-, diethyl ester; 3-Methylbutylmalonic Acid Diethyl Ester; Diethyl Iso-Pentylmalonate
EINECS	226-411-9

Quality Control

Our Diethyl Isoamylmalonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C (59°F and 77°F).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.425 - 1.435
Density (20°C)	0.970 - 0.990 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.