Description

Clomegestone is a synthetic progestogen, a member of the steroid hormone class. This high-purity active pharmaceutical ingredient (API) is critical for the development and formulation of advanced hormonal therapies. It is primarily utilized by pharmaceutical manufacturers and research institutions in the life sciences sector for its specific biological activity.

Application

• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex steroid-based pharmaceuticals.
• Hormone Research: Used as a reference standard and experimental compound in biochemical and pharmacological studies related to progesterone receptors.
• API Development: Employed in the research and development of novel progestogen-based active pharmaceutical ingredients for various therapeutic areas.
• Veterinary Medicine: Potential application in the development of hormonal treatments for animals.

Basic Information

Product Name	Clomegestone
CAS No.	5367-84-0
Molecular Formula	C22H29ClO4
Molecular Weight	392.92 g/mol
Synonyms	6-Chloro-17-hydroxy-16-methylene-3,20-dioxopregna-4,6-diene; 6-Chloro-6-dehydro-16-methylene-17α-acetoxyprogesterone; Clomegestone Acetate; SH-741; NSC-92336; 16-Methylene-6-chloro-17α-acetoxy-4,6-pregnadiene-3,20-dione
EINECS	226-341-5

Quality Control

Our Clomegestone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We can support development projects with material meeting research-grade or current Good Manufacturing Practice (cGMP) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.