Description

4-(Bromoacetyl)Pyridine Hydrobromide is a versatile and reactive bifunctional organic intermediate, crucial for constructing complex molecular architectures. Its core value lies in the presence of both a reactive bromoacetyl group and a pyridine ring, making it an essential building block for pharmaceutical research and fine chemical synthesis. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other bioactive molecules targeting the central nervous system and oncology.
• Ligand Synthesis: Used to prepare functionalized pyridine-based ligands for catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Serves as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce the 4-acetylpyridine moiety.
• Peptidomimetic & Bioconjugation: The bromoacetyl group is reactive towards thiols, enabling its use in creating peptide conjugates and bioconjugation linkers.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators.
• Material Science: Intermediate in the synthesis of organic semiconductors, photoactive compounds, and advanced polymers.

Basic Information

Product Name	4-(Bromoacetyl)Pyridine Hydrobromide
CAS No.	5349-17-7
Molecular Formula	C7H7Br2NO
Molecular Weight	280.95 g/mol
Synonyms	1-(4-Pyridinyl)-2-bromoethanone Hydrobromide; 2-Bromo-1-(4-pyridinyl)ethanone Hydrobromide; 4-Pyridyl Bromomethyl Ketone Hydrobromide; 4-Acetylpyridine, ω-bromo-, hydrobromide; p-Bromoacetylpyridine Hydrobromide; 4-(2-Bromoacetyl)pyridine Hydrobromide; ω-Bromo-4-pyridyl methyl ketone Hydrobromide
EINECS	226-310-8

Quality Control

Our 4-(Bromoacetyl)Pyridine Hydrobromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.