Description

4-Pyridineacrylic Acid is a versatile heterocyclic building block featuring both a pyridine ring and an acrylic acid moiety. This bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functional polymers. The compound, identified by CAS NO 5337-79-1, is essential for creating novel compounds with tailored electronic and biological properties.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and plant growth regulators that leverage its heterocyclic structure.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials and emissive layer components in display technologies.
• Metal-Organic Framework (MOF) Ligand: The carboxylic acid group acts as a coordination site for constructing porous materials for gas storage and catalysis.
• Polymer Modification: Incorporated as a functional monomer to impart specific chemical reactivity or polarity to polymer chains.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Heck) to introduce the pyridine-acrylate motif into target molecules.
• Chemical Research & Development: A fundamental building block in academic and industrial labs for exploring new synthetic methodologies and material properties.

Basic Information

Product Name	4-Pyridineacrylic Acid
CAS No.	5337-79-1
Molecular Formula	C8H7NO2
Molecular Weight	149.15 g/mol
Synonyms	3-(4-Pyridyl)acrylic Acid; 4-Pyridylacrylic Acid; (E)-3-(Pyridin-4-yl)acrylic Acid; trans-3-(4-Pyridyl)acrylic Acid; β-(4-Pyridyl)acrylic Acid; 4-Pyridinepropenoic Acid; 4-Vinylpyridine-3-carboxylic Acid; PAA (context-specific)
EINECS	226-258-9

Quality Control

Our 4-Pyridineacrylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	245 - 250 °C (dec.)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.