Description

Pivalic Acid (S)-2,3-Dihydroxypropyl Ester is a chiral specialty ester derived from pivalic acid and (S)-2,3-dihydroxypropyl alcohol. This compound is valued for its role as a versatile chiral building block and protecting group in sophisticated organic synthesis. It is primarily needed by research and development chemists in the pharmaceutical and fine chemical industries for the production of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key building block for constructing enantiomerically pure molecules, particularly in the development of new drugs and APIs.
• Asymmetric Catalysis & Ligand Synthesis: Used in the preparation of chiral ligands and catalysts for stereoselective chemical reactions.
• Protecting Group Chemistry: The pivaloyl (Piv) group serves as a robust protecting group for alcohols and other functional groups during multi-step syntheses.
• Fine Chemical & Agrochemical Research: Employed in the R&D of high-value specialty chemicals, including advanced agrochemicals and flavors/fragrances.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and process chemistry laboratories.

Basic Information

Product Name	Pivalic Acid (S)-2,3-Dihydroxypropyl Ester
CAS No.	5309-43-3
Molecular Formula	C8H16O4
Molecular Weight	176.21 g/mol
Synonyms	(S)-2,3-Dihydroxypropyl pivalate; (S)-1,2-Dihydroxy-3-propyl pivalate; (S)-Glyceryl pivalate; (S)-Pivaloyl glycerol; (S)-2,3-Dihydroxypropyl 2,2-dimethylpropanoate; (S)-Pivalic acid 2,3-dihydroxypropyl ester; (S)-Pivaloylglycerol
EINECS	226-158-4

Quality Control

Our Pivalic Acid (S)-2,3-Dihydroxypropyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC, optical rotation), identity confirmation (IR, NMR), and chemical purity assessment to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.