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8-(2-Hydroxy-3-Phenylpropyl)-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One CAS NO 5229-85-6


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CAS No.:5229-85-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

8-(2-Hydroxy-3-Phenylpropyl)-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One is a high-purity, complex heterocyclic organic compound featuring a spirocyclic structure with oxa-diaza functionality. This compound matters as a sophisticated chemical intermediate and pharmacological building block, enabling the synthesis of advanced molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic applications.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological receptors.
  • Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its complex, drug-like spirocyclic scaffold.
  • Chemical Synthesis: Serves as a versatile precursor for creating libraries of complex heterocycles for high-throughput screening.
  • Biochemical Research: Potential use as a ligand or probe in studying enzyme inhibition or receptor binding mechanisms.
  • Advanced Material Synthesis: Exploration into specialty polymers or organic electronic materials where its rigid structure may impart unique properties.

Basic Information

Item Detail
Product Name 8-(2-Hydroxy-3-Phenylpropyl)-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One
CAS No. 5229-85-6
Molecular Formula C17H24N2O2
Molecular Weight 288.39 g/mol
Synonyms 1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-(2-hydroxy-3-phenylpropyl)-; 8-(2-Hydroxy-3-phenylpropyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one; UNII-3J0Y1WA9BM; 3J0Y1WA9BM; Spiro[1-oxa-3,8-diazacyclopentane-4,1'-cyclopentane]-2-one, 8-(2-hydroxy-3-phenylpropyl)-; CHEMBL3183452; DTXSID80335769; NSC 113928
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Quality Control

Our 8-(2-Hydroxy-3-Phenylpropyl)-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. Comprehensive Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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