Description

11-Keto-δ-9-Norethisterone is a high-purity synthetic steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers engaged in advanced hormone-based therapeutics. The product is supplied with rigorous quality control to ensure consistency and reliability for sensitive downstream applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of advanced steroidal active pharmaceutical ingredients (APIs) and progestogens.
• Research & Development: Used in medicinal chemistry for the discovery and development of new therapeutic agents targeting hormonal pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex steroid derivatives with modified biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of steroid-based medications.

Basic Information

Product Name	11-Keto-δ-9-Norethisterone
CAS No.	5210-27-5
Molecular Formula	C₂₀H₂₄O₃
Molecular Weight	312.41 g/mol
Synonyms	11-Keto-19-Nor-17α-pregn-4-en-20-yn-3-one; 11-Oxonorgestrel; 17α-Ethynyl-17β-hydroxy-11-oxo-19-norandrost-4-en-3-one; 11-Keto Norethisterone; 11-Keto Norethindrone; δ⁹(11)-Norethisterone-11-one; 19-Nor-17α-pregn-4-en-20-yn-3,11-dione
EINECS	Contact for details

Quality Control

Our 11-Keto-δ-9-Norethisterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the stringent requirements of pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.