Description

3-Isocyanatobenzoyl Chloride is a versatile and highly reactive aromatic isocyanate derivative, serving as a critical bifunctional building block in advanced organic synthesis. Its dual functionality—combining a reactive isocyanate group with an acid chloride moiety—makes it indispensable for creating tailored polymers and fine chemicals with specific performance characteristics. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty polymer industries seeking to introduce isocyanate and amide linkages into complex molecular architectures.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing urea or carbamate functional groups.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and pesticides, where it acts as a linker to create bioactive molecules.
• Polymer & Resin Modification: Serves as a cross-linking agent and monomer for producing polyurethanes, polyamides, and other high-performance polymers with enhanced thermal or mechanical properties.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of specialized dyes and organic pigments, contributing to color fastness and stability.
• Surface Coating Agents: Incorporated into coatings and adhesives to improve durability, chemical resistance, and adhesion to substrates.
• Chemical Research & Development: A valuable reagent for exploring new organic reactions and developing novel materials in academic and industrial laboratories.

Basic Information

Product Name	3-Isocyanatobenzoyl Chloride
CAS No.	5180-79-0
Molecular Formula	C8H4ClNO2
Molecular Weight	181.58 g/mol
Synonyms	m-Isocyanatobenzoyl Chloride; 3-Isocyanatobenzoic Acid Chloride; Isocyanic Acid m-(Chlorocarbonyl)phenyl Ester; Benzoic acid, 3-isocyanato-, chloride; Meta-Isocyanatobenzoyl Chloride; 3-Carboxyphenyl Isocyanate Chloride; Isocyanatobenzoyl Chloride (meta)
EINECS	225-953-8

Quality Control

Our 3-Isocyanatobenzoyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We adhere to cGMP principles where applicable, and our quality systems support traceability and regulatory requirements for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture and to maintain product integrity. Keep away from heat, open flames, and incompatible materials such as water, alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.