Description

1-(Toluene-4-Sulfonyl)-Piperidine-3-Carboxylic Acid is a high-purity, versatile organic building block and pharmaceutical intermediate. Its value lies in its functionalized piperidine core and sulfonyl protecting group, making it a critical synthon for constructing complex molecules in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Chemical Biology Probes: Useful for creating tool compounds and probes to study biological pathways and enzyme functions.
• Academic & R&D Laboratories: A valuable reagent for synthetic organic chemistry research and method development.

Basic Information

Product Name	1-(Toluene-4-Sulfonyl)-Piperidine-3-Carboxylic Acid
CAS No.	5134-62-3
Molecular Formula	C14H19NO4S
Molecular Weight	297.37 g/mol
Synonyms	1-(4-Methylphenylsulfonyl)piperidine-3-carboxylic acid; 3-Piperidinecarboxylic acid, 1-[(4-methylphenyl)sulfonyl]-; 1-Tosylpiperidine-3-carboxylic acid; 1-(p-Toluenesulfonyl)piperidine-3-carboxylic acid; 1-(Tosyl)piperidine-3-carboxylic acid; 1-(4-Tolylsulfonyl)piperidine-3-carboxylic acid; 1-(Toluene-4-sulfonyl)piperidine-3-carboxylic acid; 5134-62-3
EINECS	Contact for details

Quality Control

Our 1-(Toluene-4-Sulfonyl)-Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.