Description

Diethyl 2-Phenylpropanedioate is a versatile diester compound, specifically the diethyl ester of phenylmalonic acid. This chemical serves as a critical synthetic intermediate and building block in advanced organic synthesis, valued for its reactive methylene group flanked by two carbonyls. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with arylacetic acid or related structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require phenyl-substituted malonate cores.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and specialty polymers where the phenylmalonate moiety is incorporated.
• Organic Synthesis Reagent: Acts as a precursor for Knoevenagel condensations, Michael additions, and other C-C bond-forming reactions in research and development.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing certain aromatic esters used in fragrance compositions.
• Ligand and Catalyst Development: Serves as a starting material for creating chelating ligands in coordination chemistry and catalysis.

Basic Information

Item	Details
Product Name	Diethyl 2-Phenylpropanedioate
CAS No.	5122-44-1
Molecular Formula	C₁₃H₁₆O₄
Molecular Weight	236.26 g/mol
Synonyms	Diethyl Phenylmalonate; Ethyl Phenylmalonate; Phenylmalonic Acid Diethyl Ester; Diethyl 2-Phenylmalonate; Propanedioic acid, 2-phenyl-, diethyl ester; Diethyl (phenyl)propanedioate; Benzylmalonic Acid Diethyl Ester
EINECS	225-852-8

Quality Control

Our Diethyl 2-Phenylpropanedioate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) detailing key parameters such as assay, impurity profile, and physical properties. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.495 - 1.505
Density (20°C)	1.10 - 1.15 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.