Description

4-Aminomethyl-1-Benzyl-Piperidin-4-Ol Dihydrochloride is a high-purity, pharmaceutically relevant piperidine derivative supplied as a dihydrochloride salt. This compound serves as a critical synthetic intermediate and building block in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting the central nervous system (CNS).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Fine Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex piperidine-based compounds and specialty chemicals.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) settings for exploratory organic synthesis and method development.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	4-Aminomethyl-1-Benzyl-Piperidin-4-Ol Dihydrochloride
CAS No.	5053-13-4
Molecular Formula	C13H20N2O · 2HCl
Molecular Weight	293.23 g/mol (Free base: 220.31 g/mol)
Synonyms	1-Benzyl-4-(aminomethyl)-4-piperidinol Dihydrochloride; 4-(Aminomethyl)-1-benzyl-4-piperidinol Dihydrochloride; 4-Piperidinol, 4-(aminomethyl)-1-benzyl-, dihydrochloride; 1-Benzyl-4-piperidinol, 4-(aminomethyl)-, dihydrochloride; 4-Aminomethyl-1-benzylpiperidin-4-ol Dihydrochloride; 4-(Aminomethyl)-1-benzyl-4-hydroxypiperidine Dihydrochloride; NSC 102627
EINECS	Contact for details

Quality Control

Our 4-Aminomethyl-1-Benzyl-Piperidin-4-Ol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.