Description

8-(p-Ethoxyphenylcarbamoylmethyl)-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One is a high-purity, specialized organic compound belonging to the spirocyclic lactam class, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring a spirocyclic core and an ethoxyphenylcarbamoyl moiety, makes it an invaluable building block for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals requiring specific structural motifs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of new drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its spirocyclic structure can contribute to novel modes of action.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	8-(p-Ethoxyphenylcarbamoylmethyl)-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One
CAS No.	5053-04-3
Molecular Formula	C18H25N3O4
Molecular Weight	347.41 g/mol
Synonyms	1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-[[(4-ethoxyphenyl)amino]carbonyl]methyl]-; 8-[(4-Ethoxyphenylcarbamoyl)methyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one; Spirocyclic Lactam Derivative; 5053-04-3; UNII-9H5I8V6F8C; 9H5I8V6F8C; 8-({[(4-ethoxyphenyl)amino]carbonyl}methyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
EINECS	Contact for details

Quality Control

Our production of 8-(p-Ethoxyphenylcarbamoylmethyl)-1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP-compliant manufacturing for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.