Description

1-Oxa-3,8-Diazaspiro(4.5)Decan 2-One is a high-purity spirocyclic heterocyclic compound, serving as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. Its unique molecular architecture, featuring fused oxazine and diazepane rings, makes it invaluable for constructing complex molecules with specific biological activity. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used as a building block for creating new generation pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Employed in the design of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for developing polymers with specialized thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: Serves as a versatile scaffold in medicinal chemistry and process chemistry for lead optimization and scale-up studies.

Basic Information

Product Name	1-Oxa-3,8-Diazaspiro(4.5)Decan 2-One
CAS No.	5052-95-9
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	2-Oxo-1-oxa-3,8-diazaspiro[4.5]decane; 1-Oxa-3,8-diazaspiro[4.5]decan-2-one; Spiro[4.5]decane-8-carboxamide, 1-oxa-3,8-diaza-2-oxo-; 8-Carbamoyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one; 5052-95-9; 1-Oxa-3,8-diazaspiro(4,5)decan-2-one
EINECS	Contact for details

Quality Control

Our 1-Oxa-3,8-Diazaspiro(4.5)Decan 2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed specifications, including assay and impurity profiles by HPLC. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.